Glenn Close
Role: Cruella de Vil
Gérard Depardieu
Role: Jean Pierre Le Pelt
Ioan Gruffudd
Role: Kevin Shepherd
Alice Evans
Role: Chloe Simon
Tim McInnerny
Role: Alonzo
Eric Idle
Role: Waddlesworth (voice)
Carol MacReady
Role: Agnes
Ian Richardson
Role: Mr. Torte
Jim Carter
Role: Detective Armstrong
David Horovitch
Role: Dr. Pavlov
Dick Brannick
Role: Pavlov's Assistant
Mike Hayley
Role: Constable
Nicholas Hutchison
Role: Reporter
Tim Willcox
Role: ITN Reporter
June Watson
Role: Prison Warden
Tony Bluto
Role: Photocopier Repairman
Tessa Vale
Role: Ticket Seller
John Styles
Role: Punch & Judy Man
Kerry Shale
Role: Le Pelt's Assistant
Thierry Lawson
Role: Le Pelt's Assistant
Hugh Futcher
Role: Brakeman
Charles Simon
Role: Lord Carnivore
Dorothea Phillips
Role: Mrs. Mirthless
Delphine Annaiis
Role: Paris Poodle Lady
Sherwood Ball
Role: Singer (uncredited)
Macéo Bhardwaj
Role: Audience Member (uncredited)
JB Blanc
Role: Police Captain (uncredited)
Ian Boo Khoo
Role: Passenger at Station (uncredited)
Julia Bridgeman
Role: Schoolgirl / Puppy (voice; uncredited)
Greg Bronson
Role: Luncheon Attendee (uncredited)
Martin Brown
Role: TV News Sound Recordist (uncredited)
Rene Costa
Role: Paparazzi (uncredited)
Leilani Holmes
Role: Orient Express Passenger (uncredited)
Karen Kennedy
Role: Social Worker / Driver (uncredited)
Suzy Kewer
Role: French Model (uncredited)
David Keyes
Role: Waddlesworth (voice; uncredited)
Jake Lanning
Role: Delivery Man (uncredited)
Jonathan Lucas
Role: Newscaster (voice; uncredited)
Jack Mason
Role: Boy on Climbing Frame (uncredited)
Ann Mills
Role: Fashion Show Editor (uncredited)
Adriana Nima
Role: Dottie (uncredited)
James Payne
Role: Taxi Driver (uncredited)
Brett Reylander
Role: Chef (uncredited)
Nigel Rixon
Role: Bus Driver (uncredited)