Don Knotts
Role: Dr. Jesse W. Heywood
Barbara Rhoades
Role: Penelope 'Bad Penny' Cushings
Jackie Coogan
Role: Matthew Basch
Ruth McDevitt
Role: Mrs. Olive Heywood
Frank McGrath
Role: Mr. Remington
Carl Ballantine
Role: Abel Swanson
Robert Yuro
Role: Arnold the Kid
Herb Voland
Role: Dr. Friedlander
Dub Taylor
Role: Pop Cushings
Dick Wilson
Role: Black Eagle (Indian chief)
Don 'Red' Barry
Role: Rev. Zachary Gant
Vaughn Taylor
Role: Rev. Longbaugh
Edward Faulkner
Role: Marshal Sam Huggins
Arthur Space
Role: Sheriff Tolliver
Greg Mullavey
Role: Phelps - Dental Student
Fred Aldrich
Role: Passerby (uncredited)
E.J. André
Role: Will Banks
John Aniston
Role: Indian (uncredited)
Argentina Brunetti
Role: Squaw (uncredited)
Claudia Bryar
Role: Mrs. Remington
Paul Bryar
Role: Man at Bar (uncredited)
Noble 'Kid' Chissell
Role: Townsman (uncredited)
William Christopher
Role: Hotel Manager (uncredited)
Frank Coghlan Jr.
Role: Man at Bar (uncredited)
Warde Donovan
Role: Townsman (uncredited)
Mickey Finn
Role: Father (uncredited)
Myron Healey
Role: Stage Passenger (uncredited)
Charles Horvath
Role: Indian Warrior (uncredited)
Clyde Howdy
Role: Man (uncredited)
I. Stanford Jolley
Role: Bearded Stage Passenger (uncredited)
Gil Lamb
Role: Slosh White - Drunk
James McHale
Role: Conductor (uncredited)
Tina Menard
Role: Squaw (uncredited)
Kathryn Minner
Role: 96-Year-Old Woman (uncredited)
Dorothy Neumann
Role: Mrs. Eva Longbaugh
Eddie Quillan
Role: Train Porter (uncredited)
Bill Quinn
Role: U.S. Marshal Arthur Bates
Rodd Redwing
Role: White Buffalo (uncredited)
Benny Rubin
Role: Man at Bar (uncredited)
Naomi Stevens
Role: Squaw (uncredited)
Boyd Stockman
Role: Stage Driver (uncredited)
Leonard Stone
Role: Bartender (uncredited)
Lorna Thayer
Role: Saloon Girl (uncredited)
Peggy Mondo
Role: Indian Woman in Stagecoach
Jim Boles
Role: Big Spring Townsman (uncredited)