Jean Hersholt
Role: Dr. John Luke
Yvonne Dionne
Role: Yvonne, a Wyatt Quintuplet
Annette Dionne
Role: Annette, a Wyatt Quintuplet
Cécile Dionne
Role: Cécile, a Wyatt Quintuplet
Émilie Dionne
Role: Émilie, a Wyatt Quintuplet
Marie Dionne
Role: Marie, a Wyatt Quintuplet
June Lang
Role: Mary MacKenzie
Slim Summerville
Role: Constable Jim Ogden
Michael Whalen
Role: Tony Luke
Dorothy Peterson
Role: Nurse Katherine Kennedy
Robert Barrat
Role: MacKenzie
Jane Darwell
Role: Mrs. Graham
John Qualen
Role: Asa Wyatt
Frank Reicher
Role: Dr. Paul Luke
Montagu Love
Role: Sir Basil Crawford
David Torrence
Role: Governor General
George Chandler
Role: Greasy
Helen Jerome Eddy
Role: Mrs. Ogden
Aileen Carlyle
Role: Mrs. Wyatt
George Meeker
Role: Dr. Wilson
J. Anthony Hughes
Role: Mike
William Benedict
Role: The Gawker
Stanley Blystone
Role: Logger (uncredited)
Sven Hugo Borg
Role: Logger (uncredited)
Harry C. Bradley
Role: Clergyman (uncredited)
Richard Carlyle
Role: Bishop (uncredited)
Horace B. Carpenter
Role: Townsman (uncredited)
Mary Carr
Role: Woman with Baby Clothes (uncredited)
William Conlon
Role: Peg-leg Walter (uncredited)
Harry Cording
Role: Logger (uncredited)
Gino Corrado
Role: Logger (uncredited)
Sidney D'Albrook
Role: Townsman (uncredited)
John Dilson
Role: City Editor (uncredited)
James Dime
Role: Townsman (uncredited)
Margaret Fielding
Role: Sir Basil's Secretary (uncredited)
Jeanne Hart
Role: Girl (uncredited)
Harry Harvey
Role: Reporter (uncredited)
Payne B. Johnson
Role: Boy with Quintuplets (uncredited)
Tom Kennedy
Role: Logger (uncredited)
Claude King
Role: Toastmaster (uncredited)
Wilfred Lucas
Role: Proprietor (uncredited)
Margaret Mann
Role: Townswoman (uncredited)
Tom McGuire
Role: Dinner Guest (uncredited)
Paul McVey
Role: Mark, a Logger (uncredited)
Edward McWade
Role: Newspaper Editor (uncredited)
William H. O'Brien
Role: Waiter in Restaurant (uncredited)
Dillon Ober
Role: Piano Player (uncredited)
Garry Owen
Role: Jerry (uncredited)
Thomas Pogue
Role: Townsman (uncredited)
Patricia Reel
Role: Child (uncredited)
Kane Richmond
Role: Logger Paying Doctor (uncredited)
Florence Roberts
Role: Grandmother (uncredited)
Joe Sawyer
Role: Joe, the Logger Lifting Log (uncredited)
Phillips Smalley
Role: Man on Dais (uncredited)
Marvin Stephens
Role: Ham Radio Operator (uncredited)
Harry Strang
Role: Logger (uncredited)
Monte Vandergrift
Role: Townsman (uncredited)
Delmar Watson
Role: Oldest Wyatt Boy (uncredited)
Cecil Weston
Role: Mother of Dying Girl (uncredited)
Charles C. Wilson
Role: George the Boat Captain (uncredited)
Harry Wilson
Role: Married Logger (uncredited)