Matthew Modine
Role: Dr. Don Francis
Alan Alda
Role: Dr. Robert Gallo
Patrick Bauchau
Role: Dr. Luc Montagnier
Nathalie Baye
Role: Dr. Françoise Barre
Christian Clemenson
Role: Dr. Dale Lawrence
David Clennon
Role: Mr. Johnstone
Phil Collins
Role: Eddi Papasano
Bud Cort
Role: Antique Shop Owner
Alex Courtney
Role: Dr. Mika Popovic
David Dukes
Role: Dr. Mervyn Silverman
Richard Gere
Role: The Choreographer
David Marshall Grant
Role: Dennis Seeley
Ronald Guttman
Role: Dr. Jean-Claude Chermann
Glenne Headly
Role: Dr. Mary Guinan
Anjelica Huston
Role: Dr. Betsy Reisz
Ken Jenkins
Role: Dr. Dennis Donohue
Richard Jenkins
Role: Dr. Marc Conant
Tchéky Karyo
Role: Dr. Willy Rozenbaum
Swoosie Kurtz
Role: Mrs. Johnstone
Jack Laufer
Role: Mrs. Johnstone
Donal Logue
Role: Bobbi Campbell
Steve Martin
Role: The Brother
Richard Masur
Role: William W. Darrow, PhD
Dakin Matthews
Role: Congressman Phil Burton
Ian McKellen
Role: Bill Kraus
Peter McRobbie
Role: Dr. Max Essex
Lawrence Monoson
Role: Chip
Jeffrey Nordling
Role: Gaetan Dugas
Saul Rubinek
Role: Dr. Jim Curran
Charles Martin Smith
Role: Dr. Harold Jaffe
Stephen Spinella
Role: Brandy Alexander
Lily Tomlin
Role: Dr. Selma Dritz
BD Wong
Role: Kico Govantes
Walter Addison
Role: Blood Bank Executive
Jill Andre
Role: Red Cross Spokesperson
Alan Barry
Role: Hemophiliac Patient
Neal Benari
Role: Dr. Tom Spira
David Dean Bottrell
Role: Man #3
Rico Bueno
Role: Bellevue Hospital Patient
Bill Carmichael
Role: Delivery Man
Christopher Carroll
Role: Dr. Aaron Kellner
Reg E. Cathey
Role: Staff Doctor #2
John Del Regno
Role: Man in Grand Central
Mogens Eckert
Role: Chief Executive (Copenhagen)
Carey Eidel
Role: Tennis Player
Robert Briscoe Evans
Role: 2nd Reporter
Richard Fancy
Role: Dr. Michael Gottlieb
Keythe Farley
Role: Lab Technician
Christopher John Fields
Role: Lawyer
Dave Florek
Role: Doughnut Shop Counterman
Niki Guluchi
Role: Sudanese Girl
Yasmine Golchan
Role: Dr. Françoise Brun-Vezinet
Patrick Gorman
Role: Charles Dauget
James Greene
Role: Dr. Alvin Freedman-Kien
Jeff Hayenga
Role: Dr. Bruce Voeller
Daniel Henning
Role: Blaine
Ike Ikediashi
Role: Sudanese Boy
Laura Innes
Role: Hemophiliac Representative
Laura James
Role: Margaret Heckler
Michael Kearns
Role: Cleve
Erasor Kemie
Role: Sudanese Student
Jack Kenny
Role: San Francisco Activist
Thomas Kopache
Role: Blood Bank Executive
Clyde Kusatsu
Role: Blood Bank Executive
Frank Li'Bay
Role: Desk Clerk
Rob LaBelle
Role: Gay Rights Activist
René Le Vant
Role: Blood Bank Executive
Anthony Lucero
Role: Mailroom Man
James Mastrantonio
Role: 8th Man
Rosemary Murphy
Role: Blood Bank Executive
Susanne Olsen
Role: Intern (Copenhagen)
Angela Paton
Role: Woman in Denver
Sierra Pecheur
Role: Female Reporter
Miguel Pérez
Role: Reporter
Martin Raymond
Role: 4th Man
Jeremy Regan
Role: Ticket Seller
Robert Martin Robinson
Role: Chief Administrator (French)
Valeri Ross
Role: Jim's Secretary
Hildur Ruriks
Role: Female Danish 2nd Executive
Sean Whitesell
Role: Country Club Attendant
Michael Winters
Role: Middle-Aged Man
William Wintersole
Role: Dr. Paul Florino
Lenny Wolpe
Role: Dr. Joseph Bove
Geoffrey Lower
Role: Dr. David Simpson
Richard Marcus
Role: Reporter (uncredited)