Hayley Mills
Role: Pollyanna
Jane Wyman
Role: Aunt Polly
Richard Egan
Role: Dr. Edmond Chilton
Karl Malden
Role: Reverend Paul Ford
Nancy Olson
Role: Nancy Furman
Adolphe Menjou
Role: Mr. Pendergast
Donald Crisp
Role: Mayor Karl Warren
Agnes Moorehead
Role: Mrs. Snow
Kevin Corcoran
Role: Jimmy Bean
James Drury
Role: George Dodds
Reta Shaw
Role: Tillie Lagerlof
Leora Dana
Role: Mrs. Ford
Anne Seymour
Role: Amelia Tarbell
Edward Platt
Role: Ben Tarbell
Mary Grace Canfield
Role: Angelica
Jenny Egan
Role: Mildred Snow
Gage Clarke
Role: Mr. Murg
Nolan Leary
Role: Mr. Thomas
Edgar Dearing
Role: Mr. Gorman
Arthur Tovey
Role: Fishing Booth Attendant (Uncredited)
Paul Frees
Role: Barker (Voice) (Uncredited)
Jack Deery
Role: Townsman (Uncredited)
Stephanie Gorman
Role: Girl Singing 'America, America' (Uncredited)
Tim Graham
Role: Orphanage Worker (Uncredited)
Signe Hack
Role: Townswoman (Uncredited)
Harry Harvey
Role: Editor (Uncredited)
Harvey Karels
Role: Party Guest (Uncredited)
Jon Lormer
Role: Mr. Geary (Uncredited)
Hans Moebus
Role: McEnerney, Dress Shop Manager (Uncredited)
William Newell
Role: Mr. Hooper (Uncredited)
Jean Ransome
Role: Townswoman (Uncredited)
Fred Rapport
Role: Townsman (Uncredited)
Charles Seel
Role: Train Conductor (Uncredited)
George Sowards
Role: Wagon Driver (Uncredited)
David Swift
Role: Fireman (Uncredited)
Paul Cristo
Role: Townsman (uncredited)
Cathy Ann Bisutti
Role: Girl Singing (uncredited)
Arthur Lovejoy
Role: Townsman (uncredited)