Woody Harrelson
Role: Dr. Michael Reynolds
Jon Seda
Role: Brandon 'Blue' Monroe
Anne Bancroft
Role: Dr. Renata Baumbauer
Alexandra Tydings
Role: Victoria Reynolds
Matt Mulhern
Role: Dr. Chip Byrnes
Talisa Soto
Role: Navajo Woman
Richard Bauer
Role: Dr. Bradford
Victor Aaron
Role: Webster Skyhorse
Lawrence Pressman
Role: Agent in Charge Collier
Michael O'Neill
Role: Agent Moreland
Harry Carey, Jr.
Role: Cashier
Carmen Dell'Orefice
Role: Arabella Reynolds
Brooke Ashley
Role: Calantha Reynolds
Andrea Roth
Role: Head Nurse
Bob Minor
Role: Deputy Lynch
Harper Roisman
Role: Mr. Vogel
Kelly Perine
Role: Fellow in Oncology
Andy Berman
Role: Fellow in Oncology
Kirsten Getchell
Role: Sally Byrnes
Emil Alexander
Role: Waiter
John Christian Graas
Role: Young Michael Reynolds
Christopher Masterson
Role: Jimmy Reynolds
Antwon Tanner
Role: Smokes
Linda M. Duenas
Role: Waitress
Tony Epper
Role: Hay Hauler
Mickey Jones
Role: Fuzzy, Biker #1
Gregory Scott Cummins
Role: Biker #2
Douglas B. Hall
Role: State Trooper
Dan B. Pastre
Role: State Trooper
Elaine Kagan
Role: Woman at Gas Station
Robert 'Bobby Z' Zajonc
Role: FBI Helicopter Pilot
Jeri Arredondo
Role: Hospital Pharmacist
Brian Bossetta
Role: Hospital Security Guard
Cynthia Allison
Role: CNN Reporter
Carolyn Tomlin
Role: Hospital Spokesperson
Brian K. Francis
Role: Navajo Boy
Alan Keller
Role: Older Highway Patrol Officer
Brett Harrelson
Role: Younger Highway Patrol Officer
Zoe Trilling
Role: Mini-Mart Cashier
Eugene Boggs
Role: Surgeon
Philip Zachary
Role: Disc Jockey
David Green
Role: First Inmate
Askia Won-Ling Jacob
Role: UCLA Student
Robert Downey Sr.
Role: Telephone Voices