Kyle Mooney
Role: James Pope
Mark Hamill
Role: Ted Mitchum
Jorge Lendeborg Jr.
Role: Spencer
Matt Walsh
Role: Greg Pope
Michaela Watkins
Role: Louise Pope
Ryan Simpkins
Role: Aubrey Pope
Greg Kinnear
Role: Detective Vogel
Alexa Demie
Role: Meredith
Jane Adams
Role: April Mitchum
Beck Bennett
Role: Detective Bander
Kate Lyn Sheil
Role: Arielle Smiles
James Anthony Green
Role: Police Officer
Kim Fischer
Role: Female Reporter
Kelly Chapman
Role: News Anchor
Nick Rutherford
Role: Brigsby Bear fan
Reagan Pineda
Role: Reality Talking Head
Kiera Milan Hendricks
Role: Young Smiles Sisters
Tim Heidecker
Role: Coach Brad
Ellery Davidson
Role: Hannah Slice
Christopher Sullivan
Role: FBI Agent
Joseph Paul Branca
Role: Space Alien
Nikolas Mikkelsen
Role: Theatre Patron
Matthew P. Watts
Role: Prison Guard
Ashlyn Brooke Anderson
Role: Wizzle Prince (uncredited)
Yvonne D Bennett
Role: Party Guest (uncredited)
Kami Christiansen
Role: Nurse (uncredited)
Paul Nathan Cuthbert
Role: Prison Visitor (uncredited)
Teresa Duran-Norvick
Role: Premiere Audience (uncredited)
Gerry Garcia
Role: (uncredited)
Angella Joy
Role: Reporter (uncredited)
Marilyn Miller
Role: Court Reporter (uncredited)
Chris Provost
Role: Prison Guard (uncredited)
Seth Williams
Role: Cameraman (uncredited)
Julio Torres
Role: Man Getting Haircut (uncredited)
