Robert De Niro
Role: John Wesley “Jack” Walsh
Charles Grodin
Role: Jonathan Mardukas aka “The Duke”
Yaphet Kotto
Role: Alonzo Mosely, Special Agent, F.B.I.
John Ashton
Role: Marvin Dorfler, Headhunter
Dennis Farina
Role: Jimmy Serrano, Chicago mobster
Joe Pantoliano
Role: Eddie Moscone, Bail Bonder
Richard Foronjy
Role: Tony Darvo, Serrano's henchman
Robert Miranda
Role: Joey, Serrano's henchman
Jack Kehoe
Role: Jerry Geisler, Tony's secretary
Wendy Phillips
Role: Gail, Jack's ex-wife
Philip Baker Hall
Role: Sidney, Chicago mobster
Tom Irwin
Role: F.B.I. Agent Perry
Jimmie Ray Weeks
Role: F.B.I. Agent Tuttle
Danielle DuClos
Role: Denise Walsh, Jack's daughter
Tom McCleister
Role: Red Wood, Bar Tender
Mary Gillis
Role: Bus Ticket Clerk
John Toles-Bey
Role: Monroe Bouchet
Thomas J. Hageboeck
Role: Sergeant Gooch
Stanley White
Role: Stanley
Scott McAfee
Role: Boy on Plane
Linda Cerasuolo
Role: Car Rental Clerk
Lois Smith
Role: Mrs. Nelson, Mardukas's Friend
Fran Brill
Role: Dana Mardukas, Jonathan's Wife
Michael Hawkins
Role: FBI Surveillance Agent #1
John Hammil
Role: FBI Surveillance Agent #2
Lou Felder
Role: Airline Pilot
Cameron Milzer
Role: Stewardess #1
Sonia M. Roberts
Role: Stewardess #2
Sam Sanders
Role: Train Porter
Paul Joseph McKenna
Role: Ohio Policeman
Rosemarie Murphy
Role: Coffee Shop Waitress
Jack N. Young
Role: Amarillo Desk Sergeant
Robert Coleman
Role: Native American
William Robbins
Role: Native American
Wilfred Netsosie
Role: Native American
Sherman L. Robbins
Role: Native American
Dale Beard Jr.
Role: Native American
Thomas Nez
Role: Native American
Richard Gonzalez
Role: Bar Cashier
Bill Fritz
Role: Bar Customer
Pete Jensen
Role: Flagstaff Police Captain
Andy Charnoki
Role: Flagstaff Sheriff
Tracey Walter
Role: Diner Counter Man
Robert Vento
Role: Serrano Bodyguard
Joe "Tippy" Zeoli
Role: Serrano Bodyguard
James Portolese
Role: Serrano Bodyguard
Armando Muniz
Role: Serrano Bodyguard
Dan York
Role: Las Vegas FBI Agent #1
Rowdy Burdick
Role: Las Vegas FBI Agent #2
Varnoy Lee
Role: Airport Porter
Bob Maroff
Role: L.A. Taxi Driver
Martin Brest
Role: Airline Ticket Clerk (uncredited)
Lisa Burnett
Role: Undercover Cop (uncredited)
George D. Miklos
Role: Airport Manager (uncredited)
Robert Minkoff
Role: Man (uncredited)
Marguerite Nocera
Role: Ticket Clerk (uncredited)
Terry Ray
Role: Deplaning Passenger (uncredited)
Jock L. Schloss
Role: Man (uncredited)
D. Danny Warhol
Role: Station Commuter (uncredited)
