Johnny Depp
Role: Donnie Brasco / Joseph D. 'Joe' Pistone
Al Pacino
Role: Benjamin 'Lefty' Ruggiero
Michael Madsen
Role: Dominick 'Sonny Black' Napolitano
Bruno Kirby
Role: Nicholas 'Nicky' Santora
Anne Heche
Role: Maggie Pistone
Zeljko Ivanek
Role: Tim Curley
Brian Tarantina
Role: Bruno
Rocco Sisto
Role: Richard 'Richie' Gazzo
Zach Grenier
Role: Dr. Berger
Gerry Becker
Role: Agent Dean Blandford FBI
Robert Miano
Role: Alphonse 'Sonny Red' Indelicato
Paul Giamatti
Role: FBI Technician
Gretchen Mol
Role: Sonny's Girlfriend
Tim Blake Nelson
Role: FBI Technician
Walt MacPherson
Role: Sheriff
Ronnie Farer
Role: Annette
Terry Serpico
Role: Strip Club Owner
Tony Lip
Role: Philip 'Philly Lucky' Giaccone
George Angelica
Role: Big Trin
Val Avery
Role: Santo Trafficante Jr.
Madison Arnold
Role: Jilly
Delanie Fitzpatrick
Role: Daughter
Katie Sagona
Role: Daughter
James McCauley
Role: FBI Agent
James Bulleit
Role: U.S. Attorney
Andrew Parks
Role: Hollman
Keenan Shimizu
Role: Japanese Maitre D'
Rocco Musacchia
Role: Trafficante's Man
Joe Francis
Role: Trafficante's Man
Sal Jenco
Role: Mare Chiaro Bartender
Billy Capucilli
Role: Communion Party Man
Laura Cahill
Role: Communion Party Woman
Doreen Murphy
Role: Mob Girlfriend
Denise Faye
Role: Mob Girlfriend
Elaine Del Valle
Role: Mob Girlfriend
John Horton
Role: FBI Director
Dan Brennan
Role: FBI Photographer
LaJuan Carter
Role: Singer
Joyce Stovall
Role: Singer
Randy Jurgensen
Role: Wiseguy
John Di Benedetto
Role: Wiseguy
Richard Zavaglia
Role: Wiseguy
Tony Ray Rossi
Role: Wiseguy
Edward Black
Role: Wiseguy
Gaetano LoGiudice
Role: Wiseguy
Carmelo Musacchia
Role: Wiseguy
Flint Beverage
Role: Kings Court Cop (uncredited)
Frank Bonsangue
Role: Sonny Red's Crew (uncredited)
Mark Todd Bruner
Role: FBI Agent (uncredited)
Teresa Giudice
Role: Shocked Stripper (uncredited)
Barry Hirschberg
Role: Background (uncredited)
Jim Lavin
Role: Arresting FBI Officer (uncredited)
Peter O'Hara
Role: Passerby (uncredited)
Antone Pagán
Role: Prison Guard for Pacino and Depp (uncredited)
Garry Pastore
Role: Carmine Galante's Bodyguard
Dale Resteghini
Role: Strip Club Patron (uncredited)
Larry Tobias
Role: Man in Bar (uncredited)
Elle Alexander
Role: Mob Girlfriend
Frankie Cee
Role: Civilian (uncredited)
