Jim Carrey
Role: Lloyd Christmas
Jeff Daniels
Role: Harry Dunne
Kathleen Turner
Role: Fraida
Rob Riggle
Role: Travis / Captain Lippincott
Tembi Locke
Role: Dr. Walcott
Paul Blackthorne
Role: Emergency Room Doctor
Patricia French
Role: Ms. Sourpuss
Steve Tom
Role: Dr. Pinchelow
Don Lake
Role: Dr. Meldman
Lindsay Ayliffe
Role: Professor Garabedian
Matthew Cardarople
Role: Inventor No. 1
Bill Murray
Role: Ice Pick
Grant James
Role: Mr. Stainer
Taylor St. Clair
Role: Mrs. Steiner
Erin Allin O'Reilly
Role: Asylum Nurse No. 1
Walt Arnett
Role: KEN Audience Member
Erika Bierman
Role: Fanny at Age 13
Kassidy Claire
Role: Fanny at Age 5
Carly Craig
Role: Young Fraida
Bryan Dilbeck
Role: Dr. Dilbeck
Dalton E. Gray
Role: Young Harry
Michael McCrudden
Role: Audience Member
June Shannon
Role: Harry's Trailer Park Wife
Maia Moss-Fife
Role: Receptionist
Jeff Sumner
Role: Convention Official
Julius Sharpe
Role: KEN Conference Attendee
Dave Walpole
Role: KEN Conference Attendee
Elizabeth Cooper
Role: Mrs. Julie James
Michael Yama
Role: Harry's Dad
Nancy Byers Farrelly
Role: Asylum Nurse #2
Derek Holland
Role: Asylum Patient
Brendan Boyle
Role: Asylum Patient
Swizz Beatz
Role: Ninja Leader
Mike Cerrone
Role: Trucker
Sean Gildea
Role: Trucker's Pal
Brett Wyman
Role: Inventor #2
Jo Helton
Role: Mrs. Snergle
Edward Barbanell
Role: Nursing Home Orderly
Mariann Neary
Role: Farmer's Wife
Jon Barinholtz
Role: Inventor No. 3
Lucas Daniels
Role: Bartender
Carter Hicks
Role: Bus Kid
Baxter Cooper Rogers
Role: Prom Date
Sandra Dorsey
Role: Stuffy Woman
Arielle Liberman
Role: Emergency Room Nurse
Jon Barry
Role: Emergency Room Orderly
Jesse Gines
Role: Emergency Room Orderly
Robin O'Neal Sorensen
Role: Emergency Medical Technician #1
Chris Randall Sorensen
Role: Emergency Medical Technician #2
Daniel Greene
Role: Wheelchair Ninja
Will Coogan
Role: Room Service Waiter
Caryle Seim
Role: Trailer Grandma
Danny Murphy
Role: Joystick Victim
Paul Bednarz
Role: KEN Convention Employee (uncredited)
Jennifer Cocker
Role: Young Inventor (uncredited)
John Deifer
Role: Mental Patient (uncredited)
Gregory Fears
Role: Man at Gas Station (uncredited)
Abigail Gamache
Role: Prom Attendee (uncredited)
William Goodrum
Role: Prom Singer (uncredited)
Walter Hendrix III
Role: Street Patron (uncredited)
Angela Kerecz
Role: Waitress (uncredited)
John Merical
Role: Neighbor (uncredited)
Rhomeyn Johnson
Role: Bus Driver
Nancy Yee
Role: Harry's Mom
