Jeff Bridges
Role: Dr. Mark Powell
Mary McCormack
Role: Rachel Powell
Alfre Woodard
Role: Claudia Villars
David Patrick Kelly
Role: Howie
Celia Weston
Role: Mrs. Archer
Ajay Naidu
Role: Dr. Chakaraborty
John Toles-Bey
Role: Russell
Kimberly Scott
Role: Joyce Trexler
Conchata Ferrell
Role: Betty McAllister
Vincent Laresca
Role: Navarro
Mark Christopher Lawrence
Role: Simms
Brian Howe
Role: Steve Becker
Tess McCarthy
Role: Natalie Powell - Age 6
Natasha Dorfhuber
Role: Gabby Powell - Age 9
Brandon de Paul
Role: Josh - Age 10
Aaron Paul
Role: Michael Powell - Age 21
William Lucking
Role: Sheriff
Kelly Connell
Role: Walter Fleen
Peter Maloney
Role: Duncan Flynn
Lance E. Nichols
Role: David Patel
Paul Linke
Role: Stuart Hessler
Christopher Jason Brown
Role: Danny Trexler
Greg Lewis
Role: Dominic McAllister
Clarke Peters
Role: Homeless Veteran
Olga Merediz
Role: Transit Officer
Joe Holt
Role: Transit Officer
Lola Pashalinski
Role: Russian Woman
Kateri Walker
Role: Sara Porter
Katya Abelski
Role: Rebecca Porter
Scott Lincoln
Role: Walker
Clebert Ford
Role: Homeless Man
Norman Alden
Role: Babbling Man
Rawle D. Lewis
Role: Security Guard
Erik LaRay Harvey
Role: Security Guard
Zofia Borucka
Role: Woman on Train
Anne Carroll
Role: Ward Patient
Lisa Cohen
Role: Ward Patient
Clete Francis
Role: Ward Patient
Valerie Giocondo
Role: Ward Patient
Pat Jankiewicz
Role: Ward Patient
Joseph Steven
Role: Ward Patient
Coco Leigh
Role: Ward Patient
Rafael Real
Role: Ward Patient
Julie Sands
Role: Ward Patient
Gene Smith
Role: Ward Patient
Curt Clendenin
Role: Hospital Patient (uncredited)
Frank Collison
Role: Screaming Man (uncredited)
Moet Meira
Role: Jennifer (uncredited)
Paulo Pascoal
Role: Thief (Uncredited)
Mark Alkofer
Role: Subway Commuter (uncredited)
Ted Hollis
Role: Ward Doctor (uncredited)
Randy Springer
Role: Lab Tech (uncredited)
