Brendan Fraser
Role: Stu Miley
Bridget Fonda
Role: Dr. Julie McElroy
John Turturro
Role: Monkeybone (voice)
Chris Kattan
Role: Organ Donor Stu
Giancarlo Esposito
Role: Hypnos
Rose McGowan
Role: Miss Kitty
Megan Mullally
Role: Kimmy Miley
Bob Odenkirk
Role: Head Surgeon
Whoopi Goldberg
Role: Death
Pat Kilbane
Role: Burger God Representative
Sandra Thigpen
Role: Alice
Wayne Wilderson
Role: Hutch
Amy Higgins
Role: Clarissa
Alan Gelfant
Role: Dr. Edelstein
Kristin Norton
Role: Nurse
Chris Hogan
Role: Bill, Bazoom Toy Representative
John Sylvain
Role: Ambulance Driver
Lou Romano
Role: Cop / Psycharist
Leon Laderach
Role: Surgeon in Nightmare
Scott Rogers
Role: Surgeon
Cris Thomas-Palomino
Role: Surgeon
Tony Panterra
Role: Surgeon
Ted Rooney
Role: Grim Reaper (voice)
Christopher Franciosa
Role: Reaper Who Takes Lulu
Fred Pierce
Role: Reaper in Death's Office
Harper Roisman
Role: Earl Biegler
Kristopher Logan
Role: Patron
Scott Workman
Role: Arnold the Super Reaper
Shawnee Free Jones
Role: Lizzie Borden
Edgar Allan Poe IV
Role: Edgar Allan Poe
Claudette Mink
Role: Typhoid Mary
Jon Bruno
Role: Man in the Dungeon / Stephen King
Owen Masterson
Role: Jack the Ripper
Jen Sung
Role: Attila the Hun
Tracy Zahoryin
Role: Model
Sunshine Deia Tutt
Role: Model
Jo Haugen Gash
Role: Model
Mie Kringelbach
Role: Model
Rex Reddick
Role: Museum Guard / Tuxedo Guard
Sybil Azur
Role: Museum Dancer
Anne Fletcher
Role: Museum Dancer
Diane Mizota
Role: Museum Dancer
Etty Lau
Role: All-Girl Band Sax Player
LaTonya Holmes
Role: All-Girl Band Percussionist
Lesli Jean Matta
Role: All-Girl Band Drummer
Dawn Solér
Role: All-Girl Band Member
Miko Watanbe
Role: All-Girl Band Member
Frankie Pine
Role: All-Girl Band Member
Anne King
Role: All-Girl Band Member
Rachen Assapiomonwait
Role: Korean Father
Veena Bidasha
Role: Statue Woman
Michael Anthony Jackson
Role: Bug Man
Arturo Gil
Role: Rat Guard
Jody St. Michael
Role: Centaur
Brian Steele
Role: Jumbo the Elephant God
Tom Fisher
Role: Community Service Cigarette Sweeper
Joseph S. Griffo
Role: BBQ Pig
Kim Timbers-Patteri
Role: Wasp Woman
Lisa Ebeyer
Role: Betty the Bovine
Mark Viniello
Role: Assbackward
Nathan Stein
Role: Sea Monster
Ed Holmes
Role: Buffalo Kuchina
Erica Gudis
Role: Party Babe Hybrid #1
Melinda Miamor
Role: Party Babe Hybrid #2
Caroline A. Rice
Role: Party Babe Hybrid #3
Joe Ranft
Role: Streetsquash Rabbit (voice)
Bruce Lanoil
Role: Streetsquash Raccoon (voice)
Debi Durst
Role: Streetsquash Snake (voice)
Phil Brotherton
Role: Subramansa (voice)
Roger L. Jackson
Role: Arnold the Super Reaper (voice)
Jym Dingler
Role: Community Service Cigarette Sweeper (voice)
Leslie Hedger
Role: Assbackward (voice)
Toby Gleason
Role: Buffalo Kachina (voice)
Allan Trautman
Role: BBQ Pig (voice)
Mike Mitchell
Role: Miss Hudiapp (voice)
Brendan Burns
Role: Detective #1
Robert 'Duckie' Carpenter
Role: Record Store Owner / Coma Victim
Thomas Haden Church
Role: Death's Assistant
Jamie Donovan
Role: Reporter #1
Roger Ferreira
Role: Visitor
Wendy Fowler
Role: Beautiful Fan
Paul Guiles
Role: Reporter #2
Harry Jay Knowles
Role: Lucky
Skyler Marshall
Role: Janitor
George Meyers
Role: Bazoom Toy Rep
Michelle Shaffer
Role: Woman with Bat
Tom Tangen
Role: Burger God Representative
