Rihanna
Role: Smurfette (voice)
James Corden
Role: No Name (voice)
Nick Offerman
Role: Ken (voice)
JP Karliak
Role: Gargamel / Razamel (voice)
Dan Levy
Role: Joel (voice)
Amy Sedaris
Role: Jaunty (voice)
Natasha Lyonne
Role: Mama Poot (voice)
Sandra Oh
Role: Moxie Smurf (voice)
Jimmy Kimmel
Role: Tardigrade (voice)
Octavia Spencer
Role: Asmodius (voice)
Nick Kroll
Role: Chernobog (voice)
Hannah Waddingham
Role: Jezebeth (voice)
Alex Winter
Role: Hefty Smurf (voice)
Maya Erskine
Role: Vanity Smurf (voice)
Billie Lourd
Role: Worry Smurf (voice)
Xolo Mariduena
Role: Brainy Smurf (voice)
Kurt Russell
Role: Ron (voice)
John Goodman
Role: Papa Smurf (voice)
Chris Miller
Role: Grouchy Smurf / Camouflage Smurf (voice)
Rachel Butera
Role: Azrael / List Maker Smurf (voice)
Conrad Vernon
Role: Butler (voice)
Tyler Peterson
Role: Bellhop (voice)
Marshmello
Role: Turtle (voice)
Chris Prynoski
Role: Quiet Smurf / Way Back There Smurf / Shark Taming Smurf (voice)
Spencer X
Role: Sound Effects Smurf (voice)
Hugo Miller
Role: Clumsy Smurf (voice)
Ryan Naylor
Role: Calendar Smurf (voice)
Jonny Manganello
Role: Baker Smurf (voice)
DJ Snake
Role: DJ Snake (voice)
Léa Elui
Role: Featured Paris Disco Dancer (voice)
Yuuki Luna
Role: Smurfette Anime (voice)
Daisuke Tsuji
Role: No Name Anime (voice)
Keisuke Hoashi
Role: Razamel Anime (voice)
