Tom Holland
Role: Peter Parker / Spider-Man
Jake Gyllenhaal
Role: Quentin Beck / Mysterio
Samuel L. Jackson
Role: Nick Fury
Marisa Tomei
Role: May Parker
Jon Favreau
Role: Happy Hogan
Jacob Batalon
Role: Ned Leeds
Tony Revolori
Role: Flash Thompson
Angourie Rice
Role: Betty Brant
Martin Starr
Role: Mr. Harrington
Jorge Lendeborg Jr.
Role: Jason Ionello
Cobie Smulders
Role: Maria Hill
Yasmin Mwanza
Role: Yasmin
Joshua Sinclair-Evans
Role: Josh
Tyler Luke Cunningham
Role: Tyler
Sebastián Viveros
Role: Sebastian
Toni Garrn
Role: The Seamstress
Peter Billingsley
Role: William Ginter Riva
Clare Dunne
Role: Victoria
Nicholas Gleaves
Role: Guterman
Claire Rushbrook
Role: Janice
J.K. Simmons
Role: J. Jonah Jameson
Dawn Michelle King
Role: E.D.I.T.H. (voice)
Jeroen van Koningsbrugge
Role: Dutch Soccer Hooligan
Michael de Roos
Role: Dutch Soccer Hooligan
Jan-Paul Buijs
Role: Dutch Soccer Hooligan
Sergio Pierattini
Role: Venetian Glassblower
Anjana Vasan
Role: Queens Reporter
Brian Law
Role: Queens Reporter
Evelyn Mok
Role: Queens Reporter
Tatiana Lunardon
Role: Italian TV Newsreader
Giada Benedetti
Role: Italian Customs Office
Lukáš Bech
Role: Helpful Dutch Man
Alessandro Giuggioli
Role: Italian Street Vendor
Petr Opava
Role: Opera Singer
Giuseppe Andriolo
Role: Caricaturist
Pat Kiernan
Role: Pat Kiernan
Shari Abdul
Role: High School Reporter (uncredited)
Mari Alexandrova
Role: Tourist in Venice (uncredited)
Kristen Alminta
Role: Police Officer (uncredited)
Vincent Angel
Role: Midtown High Student (uncredited)
Peter Arpesella
Role: Airplane Pilot (uncredited)
Lasco Atkins
Role: Salvation Army guest (uncredited)
Sitara Attaie
Role: Dutch Lady (uncredited)
Peter Bankolé
Role: Mob Boss (uncredited)
Blair Barnette
Role: Queens Reporter (uncredited)
Tuwaine Barrett
Role: Officer Bristow (extended cut)
Anna Benamati
Role: Shop Owner in Venice (uncredited)
Bruno Bilotta
Role: Mob Boss (uncredited)
Sharon Blynn
Role: Soren (uncredited)
Luigi Boccanfuso
Role: Italian Builder in Venice (uncredited)
Paolo Braghetto
Role: Poliziotto (uncredited)
Dante Brattelli
Role: High School Student (uncredited)
Graham Burton
Role: London Passerby (uncredited)
Ken Byrd
Role: Post Office Customer (uncredited)
Sokol Cahani
Role: Mob Boss (uncredited)
Darren Lee Campbell
Role: Victoria's Crew (uncredited)
Hélène Cardona
Role: Austrian Backpacker (uncredited)
Dian Cathal
Role: American Reporter (uncredited)
Jake Cerny
Role: Airport Traveler (uncredited)
Daphne Cheung
Role: Passport Clerk (uncredited)
Sam Chuck
Role: High School Student (uncredited)
Victoria Coburn
Role: Passerby (uncredited)
Kimberly Collison
Role: Charity Event Mom (uncredited)
Tiziana Coste
Role: Local Venetian (uncredited)
Jaylen Davis
Role: Tourist (uncredited)
Kristianne-Kaith Domingo
Role: Passerby (uncredited)
Andrew Dunkelberger
Role: Courier (uncredited)
Charlie Esquér
Role: Mexican Survivor (uncredited)
Ria Fend
Role: Tourist in Venice (uncredited)
Ferroz Fernandez
Role: Tourist in Venice (uncredited)
Vincent Frattini
Role: Venice Local (uncredited)
Massi Furlan
Role: Flight Attendant (uncredited)
Cynthia Garbutt
Role: Charity Dinner Guest (uncredited)
Thomas Goodridge
Role: Tourist in Venice (uncredited)
Sonia Goswami
Role: Tourist (uncredited)
Nicholle Hembra
Role: Saved Londoner (uncredited)
Michael Hennessy
Role: Hotel Guest (uncredited)
Meagan Holder
Role: Pretty Tourist (uncredited)
Patrick Doran
Role: Partygoer (uncredited)
Ruth Clarson
Role: Tourist (uncredited)
Chris Hyacinthe
Role: Sneezy Tour Guide (uncredited)
Michael Iacono
Role: Airport Kid Traveler (uncredited)
Roman Ibragimov
Role: Bar Customer (uncredited)
Theo Ip
Role: Tourist (uncredited)
Timothy Christian Jansen
Role: High School Student (uncredited)
Keon Kendrick
Role: Flight Attendant (uncredited)
Camille Kinloch
Role: Midtown High School Student (uncredited)
Michal Kubal
Role: Czech TV News Anchor (uncredited)
Hannah Kurczeski
Role: Student (uncredited)
Géraldine Lamarre
Role: Traffic Warden (uncredited)
Jimena Larraguivel
Role: Mexican Villager (uncredited)
Rich Lawton
Role: Journalist (uncredited)
Kat Leroy
Role: Czech Traditional Dancer (uncredited)
Gavin Lee Lewis
Role: Londoner (uncredited)
Patrick Loh
Role: Airport Passenger (uncredited)
Joseph Long
Role: Mob Boss (uncredited)
Ketan Majmudar
Role: Berlin Commuter (uncredited)
Tony Mardon
Role: Londoner (uncredited)
Antonín Mašek
Role: Bellboy (uncredited)
Ben Mendelsohn
Role: Talos (uncredited)
Bradley Wj Miller
Role: Passerby (uncredited)
Melissa Beth Miller
Role: Tourist (uncredited)
Anthony Molinari
Role: Mob Guy (uncredited)
Adrian Mozzi
Role: Venice Local (uncredited)
Brendan Murphy
Role: Police Officer (uncredited)
Amanda Musso
Role: Carnival Hot Girl (uncredited)
Emily Ng
Role: Italian Tourist (uncredited)
Daniel Olson
Role: Czech Guy (uncredited)
Hiten Patel
Role: British Station Staff (uncredited)
Luigi Petrazzuolo
Role: Gondolier (uncredited)
Aleksandrs Petukhovs
Role: London Passerby (uncredited)
Annie Pisapia
Role: Traveler (uncredited)
Jivan Xander Ramesh
Role: Pedestrian (uncredited)
Mike Ray
Role: Passerby (uncredited)
Sofia Renee
Role: High School Student (uncredited)
Cailan Robinson
Role: Victoria's Crew (uncredited)
Ray Rosario
Role: TSA Agent (uncredited)
Daniel Ryves
Role: Dad Collecting Kids (uncredited)
Maurice Sardison
Role: Party Goer (uncredited)
Karen-J Sear
Role: American Tourist (uncredited)
Ilya Tank Shilov
Role: Venice Tourist (uncredited)
Davina Sitaram
Role: London Tourist (uncredited)
Joakim Skarli
Role: London Tourist (uncredited)
Lucas Antoine Starrets
Role: Tourist (uncredited)
Faith Tarby
Role: Perfumed Lady (uncredited)
Emily Tebbutt
Role: Venice Tourist (uncredited)
Lesdy Vanessa
Role: Tourist (uncredited)
Jessica VanOss
Role: Student (uncredited)
Joe David Walters
Role: Pawn Shop Owner (uncredited)
Jo Wheatley
Role: Armed Security Officer (uncredited)
Rocco Wu
Role: Peter's Art Classmate (uncredited)
Samantha Mishinski
Role: Student (uncredited)
Aristou Meehan
Role: Italian Boy (uncredited)
Sean Coleman
Role: Yearbook Student (Uncredited)
